![]() A significant association was found for second-generation antipsychotics (PRR 3.44, 95% confidence interval 3.13) and lithium (PRR 2.03, ), but not for first-generation antipsychotics (PRR 0.99, ). Somnambulism was reported in 88.6% of cases and SRED in 18.1%. In most cases (77.6%), antipsychotic or lithium were the only drug class involved, and 53.3% of cases suspected quetiapine. ![]() Most patients were aged 18-64 years (62.0%), and 37.0% were men. The association between antipsychotics or lithium and somnambulism or SRED was computed using the proportional reporting ratio (PRR) and information component.Īmong the 5784 cases reporting somnambulism or SRED, 508 suspected at least 1 antipsychotic or lithium. All somnambulism or SRED reports related to antipsychotics or lithium were identified. The World Health Organization pharmacovigilance database (VigiBase), comprising >18 million adverse events, was queried. This study investigated the risk of reporting somnambulism or SRED associated with the use of antipsychotics and lithium. Recently, some cases of somnambulism or sleep-related eating disorder (SRED) have been reported in patients treated with these drugs. Vimeo Inc.Antipsychotics and lithium are widely used in psychiatry, particularly in schizophrenia and bipolar disorders. _widgetsettings, local_storage_support_test Twitter International Company, One Cumberland Place, Fenian Street, Dublin 2, D02 AX07, Ireland _osm_location, _osm_session, _osm_totp_token, _osm_welcome, _pk_id., _pk_ref., _pk_ses., qos_token Openstreetmap Foundation, St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS, United Kingdom Google Ireland Limited, Gordon House, Barrow Street, Dublin 4, Ireland Meta Platforms Ireland Limited, 4 Grand Canal Square, Dublin 2, Ireland She holds a PhD in political science from the University Clermont Auvergne. She was awarded a scholarship from the French Ministry of defense to conduct her PhD thesis on the evolution of regional multilateralism (European Union, United Nations, African Union and Regional Economic Communities) to deal with system of conflicts in sub-Saharan Africa. She regularly gives lectures (NATO Defense College, Chatham House), trainings and media interviews in Europe and Africa. She also headed the sub-Saharan Africa programme at the Institute of Strategic Research, Ecole militaire (IRSEM), French MoD think tank, in Paris.ĭr Gnanguênon was the director of War and Political reconstruction project (2012-2016), hosted by the Institut des mondes africains (IMAF) at the School for Advanced Studies in the Social Sciences (EHESS), winning project “Emergences Program” of Paris City. She was previously project officer on regional security at the French embassy in Dakar and senior researcher at the Institute of Security Studies (ISS) in Dakar. She worked as a Senior advisor consultant for the Friedrich Ebert Stiftung on African collective security mechanisms and for the French Development Agency (AFD) on Early warning systems. She also contributed to the first edition of the United Nations Office for West Africa and the Sahel (UNOWAS) Conflict Analysis Handbook. She is a political analyst, who held several positions in the French government, think tanks and advised international organizations. Amandine Gnanguênon is a visiting fellow at the European Council on Foreign Relations.
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